Center for Clinical Neuroscience at Yellowbrick

Increasingly, the use of neuroscience technology has allowed for improved understanding of complex conditions and insufficient response to treatment.  Expert clinical judgment in applying these neuroscience techniques may reveal previously undetected diagnoses or impairments, as well as “signature treatment response patterns” which inform therapeutic strategy.

The mission of the CCN is to provide a range of scientifically proven techniques to help those patients that have not responded, or not responded fully, to the typical approach to mental health problems.

About the Center for Clinical Neuroscience at Yellowbrick

Why is our treatment and philosophy unique?

In accordance with the Yellowbrick Model, the CCN approaches mental health problems from a developmental, neurobiological perspective. Traditional psychiatric techniques are supplemented by understanding how a person’s struggles are manifesting in their brain, as well as their behavior. Therapeutic recommendations are based on a holistic understanding of the patient, informed by understanding their psychology and developmental history and, as importantly, their genetics and brain function.

Yellowbrick’s CCN places a priority emphasis on a consultative, collaborative partnership with patients and their families. Professionals provide consultative expertise assisting emerging adults in making fully informed choices regarding health and well-being.

Yellowbrick’s Center for Clinical Neuroscience (CCN) features state of the art research, technologically advanced assessment and treatment:

  • Research validated diagnostic interview protocol (SCID)
  • Pharmacogenomic testing; Genetically informed psychopharmacology
    • Pharmacogenetics is the study of how an individual’s DNA affects their response to medication. Genomic mapping informs issues of dosing, efficacy, medication intolerance, and drug interactions. Findings are matched with databases that guide specific prescriptive choices.
  • Deep Transcranial Magnetic Stimulation (dTMS)
    • Yellowbrick employs multiple neuro-modulation techniques including Deep Transcranial Magnetic Stimulation (dTMS) as an FDA-approved treatment for depression that has not responded to medication. Neurofeedback allows for redirecting de-regulated neural networks to reduce anxiety, cognitive impairment, and impulsivity. Direct current stimulation relieves anxiety and improves sleep by inducing an alpha brain state. Each of these interventions is often highly effective quickly, non-invasive, and without adverse effects.
  • Neurofeedback
    • For impulse regulation, anxiety, information processing
  • ReCognition: Brain gym for cognitive enhancement
    • ReCognition is Yellowbrick’s cognitive enhancement “Brain Gym” offering online training programs strengthening cognitive processes such as attention, concentration, working memory, and problem-solving which are crucial to effective role performance.
  • Neuro-imaging: Quantitative EEG (Qeeg)
    • provides a 3D mapping of the electrical activity and networking relationships within the brain.
  • Neuro-cognitive assessment:
    • Neuro-cognitive testing examines discrete cognitive and mental processing functions like attention, working memory, executive function.
  • Respiratory Sinus Arrhythmia (RSA) Real-time autonomic dysregulation

Deep TMS - Transcranial Magnetic Stimulation

Brainsway Deep Transcranial Magnetic Stimulation (Deep TMS) System for Treatment of Major Depressive Disorder

If you are considering Brainsway Deep TMS treatment for the treatment of Depression you should review this information and discuss the information with your doctor in order to understand more about:

Introduction to Brainsway Deep TMS Treatment

You have been diagnosed with Major Depressive Disorder and your doctor has recommended treatment with the Brainsway Deep TMS Treatment to treat symptoms of your depression. Brainsway Deep TMS Treatment has been shown to be safe and effective in the treatment of patients with Major Depressive Disorder. Your Health Care Provider (psychiatrist or physician) will review your medical and depression history to help determine if Brainsway Deep TMS Treatment is appropriate for you or not. The treatment is performed under your psychiatrist’s supervision. Neither anesthesia nor sedation is required. You will be awake and alert during the treatment sessions. The treatment sessions include daily treatments for a period of 4 weeks. Each treatment session lasts approximately 20-30 minutes. Your doctor may consider further biweekly maintenance treatments in order to continue treating your depression.

How Deep TMS Treatment Works

DTMS stands for “Deep Transcranial Magnetic Stimulation”. DTMS is a non-invasive procedure, involving stimulation of a part of the brain called the Left Prefrontal Cortex. The stimulation activates the nerve cells in this region of the brain and improves depressive symptoms. The stimulation is produced by a treatment “coil” contained in a helmet. During treatment, the helmet is gently positioned on the left front side of your head, over this region of the brain. Short pulses of electricity sent through the treatment coil generate magnetic fields that turn on and off very rapidly. These magnetic fields are similar to those used in magnetic resonance imaging (MRI) systems. The magnetic field goes through the head and induces a weak electrical current that briefly activates the nerve cells in this region of the brain and improves depressive symptoms.

When Should the Brainsway Deep TMS Treatment be Used?

Indications for Use The Brainsway Deep TMS System is indicated for the treatment of depressive episodes in adult patients suffering from Major Depressive Disorder who failed to achieve satisfactory improvement from previous anti-depressant medication treatment in the current episode.

Summary Information

The Brainsway Deep TMS System has been shown to be safe and effective for the treatment of Major Depressive Disorder (MDD). You should discuss the treatment with your doctor to ensure that the Brainsway Deep TMS Treatment is the right treatment for you.

Most patients who benefit from Brainsway Deep TMS experience results by the third or fourth week of treatment. Some patients may experience results in less time. The Brainsway Deep TMS Treatment should be administered daily for four weeks, following by 12 weeks of biweekly treatment. This is the treatment schedule that has been demonstrated as safe and effective in the clinical study.

As with any antidepressant treatment, there is a risk that your depression symptoms might worsen during the Brainsway Deep TMS Treatment. Your depression symptoms might also worsen if you stopped taking antidepressant medications before starting the treatment. Inform your doctor immediately if your depression symptoms worsen.

The Brainsway Deep TMS Treatment has not been evaluated to be safe and effective for patients with suicidal ideation or who have recently attempted suicide.

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    Real-Time Treatment for Emerging Adults and their Families

    Bipolar Disorder

    A mental health condition that’s characterized by intense shifts in mood including both manic and depressive episodes.

    Major Depressive Disorder

    People living with Major Depressive Disorder, or MDD, experience episodes of depression and sadness that are debilitating to daily life.

    Anxiety Disorders

    Those living with anxiety disorders experience high levels of anxiety and stress that interfere negatively with daily life.

    Thought Disorder

    A mental health issue in which a person’s cognitive function is impaired, resulting in symptoms like experiencing challenges with conducting speech, reading and writing, and behavior.

    Personality Disorders

    Mental health disorders that negatively affect a person’s behaviors, thought patterns, and function. People diagnosed with these disorders experience challenges with managing relationships and understanding various situations.


    Post-Traumatic Stress Disorder is a mental health condition that people can develop as a result of experiencing traumatic situations, characterized by symptoms including flashbacks, avoidance behaviors, and more.


    A mental health condition that is characterized by specific symptoms of forgetfulness and lack of concentration, which makes it challenging to complete necessary tasks.

    Eating Disorders

    Mental health conditions that interfere with a person’s eating habits, thought patterns, and behaviors in negative ways.


    A mental health disorder diagnosable with the DSM-5 that is characterized by both obsessions and compulsive behaviors.